CONNECT Consortium at EUROoCS 2024 Conference
The CONNECT consortium, along with some members from the Microsystems section in Mechanical Engineering department at Eindhoven University of Technology, participated in the EUROoCS (European Organ-on-Chip Society) 2024 conference held in Milan, Italy, from July 3 to July 5, 2024.
Rahman Sabahi-Kaviani presented his poster on “Enhancing Human iPSC-Derived Neural Network Organization and Activity by Integrating Nanogrooves in Nervous System-on-Chip.” This work, co-authored by CONNECT PIs, highlighted the influence of NOA81 nanogrooves on NGN2+ iNeurons’ network orientation and electrophysiology. The research demonstrated exploration in neural network organization and functionality by incorporating nanostructured environments.
Gülden Akçay presented her poster on “Unveiling the Mechanical Dynamics of Neural Cells: A Brain Approach” In her study, the BoC incorporates significant mechanical aspects, including both static and dynamic mechanical stimuli, to explore their effects on neuronal morphology and activity. This research represents a significant step forward in our understanding of neural cell dynamics and opens new avenues for future research.
Attendance at the event was made possible through the research funding received from the European Union’s Horizon 2020 – H2020-FETPROACT-2018-01 under grant agreement No 824070. We thank all collaborators and investigators in CONNECT project for their continuous support to our work at TU/e. Gratitude also goes to Prof. Nael Nadif Kasri at RadboudUMC for providing WTC11 Ngn2+ iPSCs, which has been facilitated by the amazing cooperations among hDMT. Find more information about hDMT on their website and LinkedIn page.
EUROoCS serves as a community for researchers, industry professionals, and regulators to discuss and advance the field of organ-on-chip technology. The conference provided an excellent platform for networking, knowledge exchange, and fostering collaborations among experts in the field.